FDA Approved. Clinically Proven Xeomin®

Frown lines form when facial expressions are made as the muscle under the skin contracts. Over time, as your skin ages, these repeated expressions cause lasting frown lines. Neurotoxins, such as Xeomin®, are prescription medications that block the release of chemicals that cause these muscle contractions so frown lines are softened.

What is Xeomin®?

Xeomin® (incobotulinumtoxinA) is a prescription medication injected into muscles and used to temporarily improve the appearance of moderate to severe frown lines between the eyebrows (glabellar lines) in adults. Xeomin® contains botulinum toxin type A, a protein purified from the bacterium Clostridium botulinum.

How Does Xeomin® Work?

When you squint or frown, the muscles between your eyebrows contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines. Botulinum toxin type A – the active ingredient in Xeomin®– acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, Xeomin® can temporarily reduce the lines between your eyebrows.

Is Xeomin® Proven?

Xeomin® was proven effective in two randomized, double-blind, multicenter, placebo-controlled clinical trials of 547 healthy, adult patients. The average age of patients in the study was 46 years. Patients received 20 Units of Xeomin® and were classified as responders if they had a 2-grade improvement on a 4-point scale as assessed by the physician and patient. Using these criteria, treatment success was higher with Xeomin® than placebo on Day 30 in both studies (60% and 48% vs. 0% for placebo in both studies). Based on these trials, Xeomin® received FDA approval for use in glabellar lines in 2011.

State-Of-The-Art Manufacturing Process.

Xeomin® is made through a unique precision manufacturing process called XTRACT Technology™, that uses two filtration steps to isolate the therapeutic component of the molecule and removes the complexing/unnecessary proteins that don’t play an active role in treatment. Xeomin® is a double filtered neurotoxin. Head-to-head studies evaluating the relative risk of immunogenicity due to the presence or absence of complexing/unnecessary proteins have not been performed.

Before receiving Xeomin®, tell Dr. Turley about all of your medical conditions, including if you:

• Have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis or Lambert-Eaton syndrome)
• Have had any side effect from any other botulinum toxin in the past
• Have a breathing problem such as asthma or emphysema
• Have a history of swallowing problems or inhaling food or fluid into your lungs (aspiration)
• Have bleeding problems
• Have drooping eyelids
• Have plans to have surgery
• Have had surgery on your face
• Are pregnant or plan to become pregnant. It is not known if XEOMIN can harm your unborn baby
• Are breastfeeding or plan to breastfeed. It is not known if XEOMIN passes into breast milk

Book your Xeomin® consultation today!